Concepedia

Targeted depletion of lymphotoxin-α–expressing TH1 and TH17 cells inhibits autoimmune disease

Eugene Y. Chiang, Ganesh Kolumam, Xin Yu, Michelle Francesco, Sinisa Ivelja, Ivan Peng, Peter Gribling, Jean Shu, Wyne P. Lee, Canio J. Refino,

Nature Medicine · 2009 · 185 citations · 43 references

DOI

Concepts

References

43

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

Claire L. Langrish, Yi Chen, Wendy M. Blumenschein et al. · The Journal of Experimental Medicine · 2005 · 4K citations · Full text

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Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

Jonathan Sherlock, Yi Chen, Craig A. Murphy et al. · Nature · 2003 · 2.9K citations

, , +14

Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

Yan Zheng, Dimitry M. Danilenko, Patricia Valdez et al. · Nature · 2006 · 1.8K citations

, , +14

Divergent Pro- and Antiinflammatory Roles for IL-23 and IL-12 in Joint Autoimmune Inflammation

Craig A. Murphy, Claire L. Langrish, Yi Chen et al. · The Journal of Experimental Medicine · 2003 · 1.6K citations · Full text

, , +17

IL-17 Plays an Important Role in the Development of Experimental Autoimmune Encephalomyelitis

Yutaka Komiyama, Susumu Nakae, Taizo Matsuki et al. · The Journal of Immunology · 2006 · 1.5K citations · Full text

, , +17