Michelle Francesco

The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells

Xin Yu, Kristin Harden, Lino C. Gonzalez et al. · Nature Immunology · 2008 · 1.5K citations

Life Sciences, Cell Biology, Immunology +15

The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cells

Betty Chang, Min Huang, Michelle Francesco et al. · Arthritis Research & Therapy · 2011 · 231 citations · Full text

Medicine, Immunology, Pharmacology +17

Egress of CD19+CD5+ cells into peripheral blood following treatment with the Bruton tyrosine kinase inhibitor ibrutinib in mantle cell lymphoma patients

Betty Chang, Michelle Francesco, Martin F. M. de Rooij et al. · Blood · 2013 · 205 citations · Full text

Medicine, Immunology, Oncology +12

Targeted depletion of lymphotoxin-α–expressing TH1 and TH17 cells inhibits autoimmune disease

Eugene Y. Chiang, Ganesh Kolumam, Xin Yu et al. · Nature Medicine · 2009 · 185 citations

Life Sciences, Immunology, Pathology +16

Preclinical Efficacy and Anti-Inflammatory Mechanisms of Action of the Bruton Tyrosine Kinase Inhibitor Rilzabrutinib for Immune-Mediated Disease

Claire L. Langrish, J. Michael Bradshaw, Michelle Francesco et al. · The Journal of Immunology · 2021 · 124 citations · Full text

Life Sciences, Immunology, Pharmacology +17