Concepedia

J. Michael Bradshaw

JM

30

Publications

2.3K

Citations

24

H-Index

1998

Active since

Affiliations

Principia Biopharma (United States)(Current)

Washington University in St. Louis

Roche (United States)

Stanford University

Palo Alto Institute

J. Michael Bradshaw is an author at Principia Biopharma (United States) specializing in medicine, biochemistry, and natural sciences.

Top concepts

Publications per year

1998–2022

30

Publications

30

Prolonged and tunable residence time using reversible covalent kinase inhibitors

J. Michael Bradshaw, Jesse M. McFarland, Ville O. Paavilainen et al. · Nature Chemical Biology · 2015 · 422 citations · Full text

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An ultrasensitive Ca <sup>2+</sup> /calmodulin-dependent protein kinase II-protein phosphatase 1 switch facilitates specificity in postsynaptic calcium signaling

J. Michael Bradshaw, Yoshi Kubota, Tobias Meyer et al. · Proceedings of the National Academy of Sciences · 2003 · 196 citations · Full text

Molecular Mechanism of the Syk Activation Switch

Emily K. Tsang, Anthony M. Giannetti, David E. Shaw et al. · Journal of Biological Chemistry · 2008 · 160 citations · Full text

Investigation of phosphotyrosine recognition by the SH2 domain of the Src kinase 1 1Edited by P. E. Wright

J. Michael Bradshaw, Vesselin Mitaxov, Gabriel Waksman · Journal of Molecular Biology · 1999 · 146 citations

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Preclinical Efficacy and Anti-Inflammatory Mechanisms of Action of the Bruton Tyrosine Kinase Inhibitor Rilzabrutinib for Immune-Mediated Disease

Claire L. Langrish, J. Michael Bradshaw, Michelle Francesco et al. · The Journal of Immunology · 2021 · 108 citations · Full text

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