Anthony M. Giannetti

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

Till Maurer, Lindsay S. Garrenton, Angela Oh et al. · Proceedings of the National Academy of Sciences · 2012 · 621 citations · Full text

Distinct Pocket, Molecular Biology, Ras Gene +21

The Transferrin Receptor Modulates Hfe-Dependent Regulation of Hepcidin Expression

Paul J. Schmidt, Paul Toran, Anthony M. Giannetti et al. · Cell Metabolism · 2008 · 338 citations · Full text

Hepcidin Expression, Signal Transduction, Biochemistry +9

Specific Btk inhibition suppresses B cell– and myeloid cell–mediated arthritis

Julie A. Di Paolo, Tao Huang, Mercedesz Balázs et al. · Nature Chemical Biology · 2010 · 328 citations · Full text

Inflammation, Rheumatology, Rheumatoid Disorder +11

Structure of the BRAF-MEK Complex Reveals a Kinase Activity Independent Role for BRAF in MAPK Signaling

Jacob R. Haling, Jawahar Sudhamsu, Ivana Yen et al. · Cancer Cell · 2014 · 247 citations · Full text

Braf-mek Complex, Signal Transduction, Signaling Pathway +7

Antagonists Induce a Conformational Change in cIAP1 That Promotes Autoubiquitination

Erin C. Dueber, Allyn J. Schoeffler, Andreas Lingel et al. · Science · 2011 · 225 citations

Protein Function, Molecular Physiology, Signal Transduction +15