Lindsay S. Garrenton

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

Till Maurer, Lindsay S. Garrenton, Angela Oh et al. · Proceedings of the National Academy of Sciences · 2012 · 630 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Pheromone-induced anisotropy in yeast plasma membrane phosphatidylinositol-4,5- <i>bis</i> phosphate distribution is required for MAPK signaling

Lindsay S. Garrenton, Christopher J. Stefan, Michael A. McMurray et al. · Proceedings of the National Academy of Sciences · 2010 · 102 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Function of the MAPK scaffold protein, Ste5, requires a cryptic PH domain

Lindsay S. Garrenton, Susan L. Young, Jeremy Thorner · Genes & Development · 2006 · 60 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Nucleus-Specific and Cell Cycle-Regulated Degradation of Mitogen-Activated Protein Kinase Scaffold Protein Ste5 Contributes to the Control of Signaling Competence

Lindsay S. Garrenton, Andreas Braunwarth, Stefan Irniger et al. · Molecular and Cellular Biology · 2008 · 38 citations

Life Sciences, Cell Biology, Molecular Biology +17

Abstract 3595: RMC-6291, a next-generation tri-complex KRASG12C(ON) inhibitor, outperforms KRASG12C(OFF) inhibitors in preclinical models of KRASG12C cancers

Robert J. Nichols, Yu Chi Yang, Jim Cregg et al. · Cancer Research · 2022 · 34 citations

Medicine, Oncology, Pharmacology +17