Angela Oh

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

Till Maurer, Lindsay S. Garrenton, Angela Oh et al. · Proceedings of the National Academy of Sciences · 2012 · 621 citations · Full text

Distinct Pocket, Molecular Biology, Ras Gene +21

Structural basis for dual-mode inhibition of the ABC transporter MsbA

Hoangdung Ho, Anh Miu, Mary Kate Alexander et al. · Nature · 2018 · 173 citations

Molecular Pharmacology, Signal Transduction, Molecular Physiology +9

Novel Staphylococcal Glycosyltransferases SdgA and SdgB Mediate Immunogenicity and Protection of Virulence-Associated Cell Wall Proteins

Wouter L. W. Hazenbos, Kimberly K. Kajihara, Richard Vandlen et al. · PLoS Pathogens · 2013 · 86 citations · Full text

Microbial Pathogens, Glycobiology, Immunology +16

Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-p <i>K</i> _a Polar Moiety

Chudi Ndubaku, James J. Crawford, Joy Drobnick et al. · ACS Medicinal Chemistry Letters · 2015 · 81 citations · Full text

Structure-Based Discovery of Novel Amide-Containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors

Xiaozhang Zheng, Paul Bauer, Timm Baumeister et al. · Journal of Medicinal Chemistry · 2013 · 80 citations · Full text