Canio J. Refino

The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells

Xin Yu, Kristin Harden, Lino C. Gonzalez et al. · Nature Immunology · 2008 · 1.4K citations

T Cell Activation, Signal Transduction, Autoimmune Disease +12

Targeted depletion of lymphotoxin-α–expressing TH1 and TH17 cells inhibits autoimmune disease

Eugene Y. Chiang, Ganesh Kolumam, Xin Yu et al. · Nature Medicine · 2009 · 183 citations

Immune Regulation, Immunology, Immunologic Mechanism +16

New Variant of Human Tissue Plasminogen Activator (TPA) With Enhanced Efficacy and Lower Incidence of Bleeding Compared With Recombinant Human TPA

Claude R. Benedict, Canio J. Refino, Bruce A. Keyt et al. · Circulation · 1995 · 179 citations

IL-17RC Is Required for IL-17A– and IL-17F–Dependent Signaling and the Pathogenesis of Experimental Autoimmune Encephalomyelitis

Yan Hu, Naruhisa Ota, Ivan Peng et al. · The Journal of Immunology · 2010 · 149 citations · Full text

Immunodeficiencies, Immunology, Immune Regulation +21

Orally Active Fibrinogen Receptor Antagonists. 2. Amidoximes as Prodrugs of Amidines

Thomas Weller, Leo Alig, Maureen H. Beresini et al. · Journal of Medicinal Chemistry · 1996 · 120 citations · Full text