Biphenyl-indanone A, a Positive Allosteric Modulator of the Metabotropic Glutamate Receptor Subtype 2, Has Antipsychotic- and Anxiolytic-Like Effects in Mice

The use of a plus-maze to measure anxiety in the mouse

Richard G. Lister · Psychopharmacology · 1987 · 2.6K citations

Nursing, Behavioral Sciences, Psychology +6

A Novel Selective Positive Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Has in Vivo Activity and Antipsychotic-Like Effects in Rat Behavioral Models

Gene G. Kinney, Julie A. O’Brien, Wei Lemaire et al. · Journal of Pharmacology and Experimental Therapeutics · 2005 · 299 citations

Life Sciences, Neuroscience, Pharmacology +17

N-desmethylclozapine, an allosteric agonist at muscarinic 1 receptor, potentiates N-methyl- <scp>d</scp> -aspartate receptor activity

Cyrille Sur, Pierre Mallorga, Marion Wittmann et al. · Proceedings of the National Academy of Sciences · 2003 · 291 citations · Full text

Medicine, Pharmacology, Psychiatry +16

Anxiolytic and Side-Effect Profile of LY354740: A Potent, Highly Selective, Orally Active Agonist for Group II Metabotropic Glutamate Receptors

David R. Helton, J P Tizzano, James A. Monn et al. · Journal of Pharmacology and Experimental Therapeutics · 1998 · 282 citations

Medicine, Neuroscience, Pharmacology +15

Activation of the genetically defined m1 muscarinic receptor potentiates <i>N</i> -methyl- <scp>d</scp> -aspartate (NMDA) receptor currents in hippocampal pyramidal cells

Michael J. Marino, Susan T. Rouse, Allan I. Levey et al. · Proceedings of the National Academy of Sciences · 1998 · 274 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17