IL-6-mediated Th17 differentiation through RORγt is essential for the initiation of experimental autoimmune myocarditis - Concepedia

Concepedia

Publication | Closed Access

IL-6-mediated Th17 differentiation through RORγt is essential for the initiation of experimental autoimmune myocarditis

80

Citations

23

References

2011

Year

Tomomi Yamashita, Tomohiko Iwakura, Kazuki Matsui, Haruyo Kawaguchi, Masanori Obana, Akiko Hayama, Makiko Maeda, Yasukatsu Izumi, Issei Komuro, Yoshiyuki Ohsugi,

Cardiovascular Research

Abstract

IL-6-mediated induction of Th17 cells is critical for the onset of EAM, but not for its progression. IL-6/Th17 signalling could be a promising therapeutic target for the prevention of myocardial inflammation.

References

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