Th17 Effector Function is a distinct immunological mechanism characterized by the production of interleukin-17 and other pro-inflammatory cytokines by T helper 17 cells, which mediates host defense against extracellular pathogens and contributes to autoimmune inflammation, thereby distinguishing it from other effector T cell functions through its unique cytokine profile and pathological roles.
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A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
Heon Park, Zhaoxia Li, Xuexian O. Yang et al. · Nature Immunology · 2005 · 4.2K citations · Full text
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