Yoshiyuki Ohsugi

IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis

Satoshi Serada, Minoru Fujimoto, Masahiko Mihara et al. · Proceedings of the National Academy of Sciences · 2008 · 342 citations · Full text

T-regulatory Cell, Immune Regulation, Immunology +18

Tocilizumab inhibits signal transduction mediated by both mIL-6R and sIL-6R, but not by the receptors of other members of IL-6 cytokine family

Masahiko Mihara, Keiko Kasutani, Makoto Okazaki et al. · International Immunopharmacology · 2005 · 318 citations

Inflammation, Il-6 Cytokine Family, Cytokine +14

Reshaping a human antibody to inhibit the interleukin 6-dependent tumor cell growth.

Koh Sato, Masayuki Tsuchiya, José W. Saldanha et al. · PubMed · 1993 · 277 citations

Pm-1 Antibody, Cancer Immunosurveillance, Human Antibody +11

Blockage of interleukin-6 receptor ameliorates joint disease in murine collagen-induced arthritis

Nobuhiro Takagi, Masahiko Mihara, Yoichiro Moriya et al. · Arthritis & Rheumatism · 1998 · 273 citations

Interleukin‐6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses

Minoru Fujimoto, Satoshi Serada, Masahiko Mihara et al. · Arthritis & Rheumatism · 2008 · 218 citations