Masahiko Mihara

A Resorcylic Acid Lactone, 5Z-7-Oxozeaenol, Prevents Inflammation by Inhibiting the Catalytic Activity of TAK1 MAPK Kinase Kinase

Jun Ninomiya‐Tsuji, Taisuke Kajino, Koichiro Ono et al. · Journal of Biological Chemistry · 2003 · 418 citations · Full text

Medicine, Molecular Biology, Pharmacology +17

IL-6 trans-signalling directly induces RANKL on fibroblast-like synovial cells and is involved in RANKL induction by TNF-  and IL-17

Misato Hashizume, Naohiko Hayakawa, Masahiko Mihara · Lara D. Veeken · 2008 · 356 citations

Life Sciences, Cell Biology, Immunology +17

IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis

Satoshi Serada, Minoru Fujimoto, Masahiko Mihara et al. · Proceedings of the National Academy of Sciences · 2008 · 344 citations · Full text

Life Sciences, Immunology, Neuroscience +17

Tocilizumab inhibits signal transduction mediated by both mIL-6R and sIL-6R, but not by the receptors of other members of IL-6 cytokine family

Masahiko Mihara, Keiko Kasutani, Makoto Okazaki et al. · International Immunopharmacology · 2005 · 323 citations

Life Sciences, Immunology, Pharmacology +14

Blockade of interleukin-6 signaling augments regulatory T-cell reconstitution and attenuates the severity of graft-versus-host disease

Rupali Das, Richard Komorowski, Amy Beres et al. · Blood · 2009 · 289 citations · Full text

Life Sciences, Cell Biology, Immunology +12