Identification of benzimidazole-based inhibitors of the mitogen activated kinase-5 signaling pathway

Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase Kinase

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A quantitative analysis of kinase inhibitor selectivity

Mazen W. Karaman, Sanna Herrgård, Daniel K. Treiber et al. · Nature Biotechnology · 2008 · 2.4K citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

A small molecule–kinase interaction map for clinical kinase inhibitors

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Pharmacy, Medicinal Chemistry, Molecular Biology +12

An Insulin-Stimulated Protein Kinase Similar to Yeast Kinases Involved in Cell Cycle Control

Teri G. Boulton, George D. Yancopoulos, Jill S. Gregory et al. · Science · 1990 · 711 citations

Life Sciences, Biochemistry, Molecular Biology +14

Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition

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Life Sciences, Biochemistry, Molecular Biology +9