Concepedia

Inhibitor Classification

Inhibitor Classification is a systematic framework in pharmacological research that categorizes cytochrome P450 inhibitors based on their mechanistic properties, potency, and specificity to distinguish their biochemical interactions and predict drug-drug interaction risks.

635

Publications

32.9K

Citations

4.8K

Authors

843

Institutions

Publications per year

2017–2026

134

Parents

Publications

635

The specificities of protein kinase inhibitors: an update

Jenny Bain, Hilary McLauchlan, Matthew Elliott et al. · Biochemical Journal · 2003 · 1.4K citations · Full text

, , +11

Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity

Cai‐Hong Yun, Titus J. Boggon, Yiqun Li et al. · Cancer Cell · 2007 · 1.2K citations · Full text

, , +15

THE CONDUCT OF IN VITRO AND IN VIVO DRUG-DRUG INTERACTION STUDIES: A PHARMACEUTICAL RESEARCH AND MANUFACTURERS OF AMERICA (PhRMA) PERSPECTIVE

Thorir D. Bjornsson, John T. Callaghan, Heidi J. Einolf et al. · Drug Metabolism and Disposition · 2003 · 784 citations

, , +17

A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models

Elayne Chan-Penebre, Kristy G. Kuplast, Christina R. Majer et al. · Nature Chemical Biology · 2015 · 546 citations

, , +8

Tumor inhibitors. 69. Structure-cytotoxicity relations among the sesquiterpene lactones

S. Morris Kupchan, M. Allan Eakin, A. M. THOMAS · Journal of Medicinal Chemistry · 1971 · 485 citations

, , +16

1–5 of 635

Authors

4.8K

  1. RW
    Rolf W. Hartmann

    Saarland University, Germany

    12 publications · 522 citations

    11

    h-index

  2. SL
    Stefan Laufer

    University of Tübingen, Germany

    9 publications · 625 citations

    9

    h-index

  3. BS
    Brian S. J. Blagg

    University of Kansas, United States

    7 publications · 332 citations

    7

    h-index

  4. AM
    Antonello Mai

    Sapienza University of Rome, Italy

    6 publications · 395 citations

    6

    h-index

  5. TJ
    Tarun Jha

    Jadavpur University, India

    6 publications · 140 citations

    6

    h-index

1–5 of 4.8K

Institutions

843

  1. Pfizer (United States)

    New York, United States

    19 h-index

    266 publications

    17.5K citations

  2. Bristol-Myers Squibb (United States)

    New York, United States

    12 h-index

    153 publications

    8.7K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    12 h-index

    56 publications

    3.1K citations

  4. Chinese Academy of Sciences

    Beijing, China

    11 h-index

    74 publications

    2.3K citations

  5. Amgen (United States)

    Thousand Oaks, United States

    11 h-index

    206 publications

    10.4K citations

  6. Saarland University

    Saarbrücken, Germany

    11 h-index

    55 publications

    3.1K citations

  7. Shanghai Institute of Materia Medica

    Pudong, China

    11 h-index

    59 publications

    1.7K citations

  8. GlaxoSmithKline (United Kingdom)

    London, United Kingdom

    10 h-index

    137 publications

    5.3K citations

1–8 of 843

Venues

  1. Journal of Medicinal Chemistry

    112 publications · 6.8K citations

    52

    h-index

  2. Bioorganic & Medicinal Chemistry Letters

    99 publications · 3.8K citations

    36

    h-index

  3. Bioorganic & Medicinal Chemistry

    42 publications · 1.7K citations

    24

    h-index

  4. European Journal of Medicinal Chemistry

    30 publications · 1K citations

    21

    h-index

  5. ACS Medicinal Chemistry Letters

    20 publications · 962 citations

    17

    h-index

1–5