Shuyan Yi

Crystal structures of human glycine receptor α3 bound to a novel class of analgesic potentiators

Xin Huang, P.L. Shaffer, Shawn Ayube et al. · Nature Structural & Molecular Biology · 2016 · 124 citations

Medicine, Medicinal Chemistry, Pharmacology +17

The Discovery and Hit-to-Lead Optimization of Tricyclic Sulfonamides as Potent and Efficacious Potentiators of Glycine Receptors

Howard Bregman, Jeffrey R. Simard, Kristin L. Andrews et al. · Journal of Medicinal Chemistry · 2016 · 40 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery and optimization of potent and selective imidazopyridine and imidazopyridazine mTOR inhibitors

Emily A. Peterson, Alessandro A. Boezio, Paul S. Andrews et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 36 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Design, synthesis, and testing of an 6-O-linked series of benzimidazole based inhibitors of CDK5/p25

Prashi Jain, Patrick T. Flaherty, Shuyan Yi et al. · Bioorganic & Medicinal Chemistry · 2010 · 21 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Identification of benzimidazole-based inhibitors of the mitogen activated kinase-5 signaling pathway

Patrick T. Flaherty, Ishveen Chopra, Prashi Jain et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 18 citations

Pharmacy, Medicinal Chemistry, Pharmacology +7