Concepedia

P.L. Shaffer

PS

Statistics

Publications

26

Citations

2.5K

H-Index

21

Active since

2002

Affiliations

Amgen (United States)(Current)

Janssen (United States)

Duke Medical Center

Duke University Hospital

MSM Protein Technologies (United States)

P.L. Shaffer is an author at Amgen (United States) specializing in medicine, natural sciences, and biochemistry.

Top concepts

MedicineBiochemistryNatural SciencesMolecular BiologyPharmacologyDrug DiscoveryStructural BiologyMolecular PharmacologyMedicinal ChemistrySignal Transduction

Publications per year

2002–2024

26

Publications

26

Structural basis of androgen receptor binding to selective androgen response elements

P.L. Shaffer, Arif Jivan, D.E. Dollins et al. · Proceedings of the National Academy of Sciences · 2004 · 401 citations · Full text

Androgen Receptor, Crystal Structure, Systems Biology +15

Structure and Mechanism of a Na <sup>+</sup> -Independent Amino Acid Transporter

P.L. Shaffer, April Goehring, Aruna Shankaranarayanan et al. · Science · 2009 · 315 citations · Full text

Protein Chemistry, Crystal Structure, Biochemistry +13

Discovery of AMG 232, a Potent, Selective, and Orally Bioavailable MDM2–p53 Inhibitor in Clinical Development

Daqing Sun, Zhihong Li, Yosup Rew et al. · Journal of Medicinal Chemistry · 2014 · 290 citations · Full text

Crystal structure of human glycine receptor-α3 bound to antagonist strychnine

Xin Huang, Hao Chen, Klaus Michelsen et al. · Nature · 2015 · 236 citations

Molecular Pharmacology, Crystal Structure, Biochemistry +6

Structural basis of VDR-DNA interactions on direct repeat response elements

P.L. Shaffer · The EMBO Journal · 2002 · 136 citations · Full text

Chromatin, Natural Sciences, Dna Analysis +8

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