Klaus Michelsen

Crystal structure of human glycine receptor-α3 bound to antagonist strychnine

Xin Huang, Hao Chen, Klaus Michelsen et al. · Nature · 2015 · 236 citations

Molecular Pharmacology, Crystal Structure, Biochemistry +6

Structure-Based Design of Novel Inhibitors of the MDM2–p53 Interaction

Yosup Rew, Daqing Sun, Felix González-López de Turiso et al. · Journal of Medicinal Chemistry · 2012 · 166 citations · Full text

Discovery and Optimization of Chromenotriazolopyrimidines as Potent Inhibitors of the Mouse Double Minute 2−Tumor Protein 53 Protein−Protein Interaction

John G. Allen, Matthew P. Bourbeau, G. Erich Wohlhieter et al. · Journal of Medicinal Chemistry · 2009 · 147 citations · Full text

From Fragment Screening to In Vivo Efficacy: Optimization of a Series of 2-Aminoquinolines as Potent Inhibitors of Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1)

Yuan Cheng, Ted Judd, Michael D. Bartberger et al. · Journal of Medicinal Chemistry · 2011 · 136 citations · Full text

Crystal structures of human glycine receptor α3 bound to a novel class of analgesic potentiators

Xin Huang, P.L. Shaffer, Shawn Ayube et al. · Nature Structural & Molecular Biology · 2016 · 122 citations

Molecular Pharmacology, Biochemistry, G Protein-coupled Receptor +9