G. Erich Wohlhieter

A Study on the Application and Use of Artificial Intelligence to Support Drug Development

Mary Jo Lamberti, Michael Wilkinson, Bruce A. Donzanti et al. · Clinical Therapeutics · 2019 · 159 citations

Medicine, Pharmacology, Artificial Intelligence +13

Discovery and Optimization of Chromenotriazolopyrimidines as Potent Inhibitors of the Mouse Double Minute 2−Tumor Protein 53 Protein−Protein Interaction

John G. Allen, Matthew P. Bourbeau, G. Erich Wohlhieter et al. · Journal of Medicinal Chemistry · 2009 · 147 citations · Full text

Medicine, Oncology, Pharmacology +13

Cytochrome P450-Mediated Epoxidation of 2-Aminothiazole-Based AKT Inhibitors: Identification of Novel GSH Adducts and Reduction of Metabolic Activation through Structural Changes Guided by in Silico and in Vitro Screening

Raju Subramanian, Matthew R. Lee, John G. Allen et al. · Chemical Research in Toxicology · 2010 · 30 citations

Medicine, Medicinal Chemistry, Pharmacology +16

2-Aminothiadiazole inhibitors of AKT1 as potential cancer therapeutics

Qingping Zeng, Matthew P. Bourbeau, G. Erich Wohlhieter et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 24 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14