Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase Kinase

Margaret Favata, Kurumi Y. Horiuchi, Elizabeth J. Manos, +11

Journal of Biological Chemistry

MEK inhibitors: The chemistry and biological activity of U0126, its analogs, and cyclization products

John V. Duncia, Joseph B. Santella, C. Anne Higley, +22

Bioorganic & Medicinal Chemistry Letters

Biological ActivityMek InhibitorsMedicinal ChemistryBiochemistryNatural Sciences +10

Dnmt2 functions in the cytoplasm to promote liver, brain, and retina development in zebrafish

Kunal Rai, Stephanie Chidester, Chad V. Zavala, +5

Genes & Development

Zebrafish screen identifies novel compound with selective toxicity against leukemia

Suzanne Ridges, Will L. Heaton, Deepa Joshi, +23

Blood

Zebra Fish Dnmt1 and Suv39h1 Regulate Organ-Specific Terminal Differentiation during Development

Kunal Rai, Lincoln Nadauld, Stephanie Chidester, +5

Molecular and Cellular Biology

Histone ModificationsDirect Histone MethylationEpigenetic ChangeGeneticsDna Methylation +23

APRIL/TRDL-1, a tumor necrosis factor-like ligand, stimulates cell death.

Kimberly M. Kelly, Elizabeth J. Manos, Gitte S. Jensen, +2

PubMed

InflammationCancer ResearchTumor Necrosis FactorSignaling PathwayTnf Family Members +12

Microarray analysis of lipopolysaccharide-treated human neutrophils

Kenneth C. Malcolm, Patrick Arndt, Elizabeth J. Manos, +2

American Journal of Physiology-Lung Cellular and Molecular Physiology

Inflammatory Lung DiseaseImmunologyPathologyInnate ImmunityInflammation +14

The Tumor Suppressor Adenomatous Polyposis Coli and Caudal Related Homeodomain Protein Regulate Expression of Retinol Dehydrogenase L

Cicely A. Jette, Peter Peterson, Imelda T. Sandoval, +4

Journal of Biological Chemistry

Retinoic AcidPathologyCell ProliferationCancer BiologyMammary Gland Development +15

Adenomatous Polyposis Coli Control of C-terminal Binding Protein-1 Stability Regulates Expression of Intestinal Retinol Dehydrogenases

Lincoln Nadauld, Reid A. Phelps, Brent C. Moore, +8

Journal of Biological Chemistry

Inhibition of MAP Kinase Kinase (MEK) Results in an Anti-inflammatory Response in Vivo

Bruce Jaffee, Elizabeth J. Manos, Robert J. Collins, +5

Biochemical and Biophysical Research Communications

InflammationCytokineAnti-inflammatorySignal TransductionAutoimmune Disease +10