C. Anne Higley

MEK inhibitors: The chemistry and biological activity of U0126, its analogs, and cyclization products

John V. Duncia, Joseph B. Santella, C. Anne Higley et al. · Bioorganic & Medicinal Chemistry Letters · 1998 · 404 citations · Full text

Biological Activity, Mek Inhibitors, Medicinal Chemistry +12

Discovery of an Orally Active Series of Isoxazoline Glycoprotein IIb/IIIa Antagonists

Chu‐Biao Xue, John Wityak, Thais M. Sielecki et al. · Journal of Medicinal Chemistry · 1997 · 64 citations · Full text

Pharmaceutical Science, Orally Active Series, Glycobiology +17

Synthesis and Evaluation of Indenopyrazoles as Cyclin-Dependent Kinase Inhibitors. 3. Structure Activity Relationships at C3

Eddy W. Yue, C. Anne Higley, Susan V. DiMeo et al. · Journal of Medicinal Chemistry · 2002 · 47 citations · Full text

Potent Analogues, Molecular Pharmacology, Medicinal Chemistry +15

Pyrazoles, 1,2,4-triazoles, and tetrazoles as surrogates for cis-amide bonds in boronate ester thrombin inhibitors

John V. Duncia, Joseph B. Santella, C. Anne Higley et al. · Bioorganic & Medicinal Chemistry Letters · 1998 · 38 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +7

Synthesis and evaluation of indenopyrazoles as cyclin-dependent kinase inhibitors. Part 4: Heterocycles at C3

Eddy W. Yue, Susan V. DiMeo, C. Anne Higley et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 38 citations · Full text

Cyclin-dependent Kinase Inhibitors, Medicinal Chemistry, Heterocyclic +8