Eddy W. Yue

Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity

Xiangdong Liu, Niu Shin, Holly K. Koblish et al. · Blood · 2010 · 552 citations · Full text

INCB24360 (Epacadostat), a Highly Potent and Selective Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitor for Immuno-oncology

Eddy W. Yue, Richard Sparks, Padmaja Polam et al. · ACS Medicinal Chemistry Letters · 2017 · 290 citations · Full text

Hydroxyamidine Inhibitors of Indoleamine-2,3-dioxygenase Potently Suppress Systemic Tryptophan Catabolism and the Growth of IDO-Expressing Tumors

Holly K. Koblish, Michael Hansbury, Kevin Bowman et al. · Molecular Cancer Therapeutics · 2010 · 243 citations · Full text

Discovery of Potent Competitive Inhibitors of Indoleamine 2,3-Dioxygenase with in Vivo Pharmacodynamic Activity and Efficacy in a Mouse Melanoma Model

Eddy W. Yue, Brent Douty, Brian Wayland et al. · Journal of Medicinal Chemistry · 2009 · 216 citations · Full text

Pharmacotherapy, Vivo Pharmacodynamic Activity, Pharmaceutical Chemistry +17

An Olefin Metathesis Based Strategy for the Construction of the JKL, OPQ, and UVW Ring Systems of Maitotoxin

K. C. Nicolaou, Maarten H. D. Postema, Eddy W. Yue et al. · Journal of the American Chemical Society · 1996 · 104 citations

Molecular Sciences, Engineering, Heterocyclic +12