Padmaja Polam

Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity

Xiangdong Liu, Niu Shin, Holly K. Koblish et al. · Blood · 2010 · 559 citations · Full text

Medicine, Immunology, Oncology +14

INCB24360 (Epacadostat), a Highly Potent and Selective Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitor for Immuno-oncology

Eddy W. Yue, Richard Sparks, Padmaja Polam et al. · ACS Medicinal Chemistry Letters · 2017 · 296 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +8

Structure-Based Design and Discovery of Protein Tyrosine Phosphatase Inhibitors Incorporating Novel Isothiazolidinone Heterocyclic Phosphotyrosine Mimetics

Andrew P. Combs, Eddy W. Yue, Michael J. Bower et al. · Journal of Medicinal Chemistry · 2005 · 102 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Potent Benzimidazole Sulfonamide Protein Tyrosine Phosphatase 1B Inhibitors Containing the Heterocyclic ( <i>S</i> )-Isothiazolidinone Phosphotyrosine Mimetic

Andrew P. Combs, Wenyu Zhu, Matthew L. Crawley et al. · Journal of Medicinal Chemistry · 2006 · 85 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Structural Basis for Inhibition of Protein-tyrosine Phosphatase 1B by Isothiazolidinone Heterocyclic Phosphonate Mimetics

Lucie Gonneville, Milton C. Hillman, Mary Becker-Pasha et al. · Journal of Biological Chemistry · 2006 · 85 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17