Lucie Gonneville

Structure-Based Design and Discovery of Protein Tyrosine Phosphatase Inhibitors Incorporating Novel Isothiazolidinone Heterocyclic Phosphotyrosine Mimetics

Andrew P. Combs, Eddy W. Yue, Michael J. Bower et al. · Journal of Medicinal Chemistry · 2005 · 101 citations · Full text

Molecular Docking, Crystal Structure, Medicinal Chemistry +13

Potent Benzimidazole Sulfonamide Protein Tyrosine Phosphatase 1B Inhibitors Containing the Heterocyclic ( <i>S</i> )-Isothiazolidinone Phosphotyrosine Mimetic

Andrew P. Combs, Wenyu Zhu, Matthew L. Crawley et al. · Journal of Medicinal Chemistry · 2006 · 85 citations · Full text

Structural Basis for Inhibition of Protein-tyrosine Phosphatase 1B by Isothiazolidinone Heterocyclic Phosphonate Mimetics

J. Paul, Lucie Gonneville, Milton C. Hillman et al. · Journal of Biological Chemistry · 2006 · 83 citations · Full text

Structural Insights into the Design of Nonpeptidic Isothiazolidinone-containing Inhibitors of Protein-tyrosine Phosphatase 1B

J. Paul, Lucie Gonneville, Milton C. Hillman et al. · Journal of Biological Chemistry · 2006 · 60 citations · Full text

Isothiazolidinone inhibitors of PTP1B containing imidazoles and imidazolines

Brent Douty, Brian Wayland, J. Paul et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 58 citations · Full text

Isothiazolidinone Inhibitors, Medicinal Chemistry, Biochemistry +8