Concepedia

Brian Wayland

BW

10

Publications

972

Citations

10

H-Index

2001

Active since

Affiliations

Incyte (United States)(Current)

Experimental Station

The University of Texas at Arlington

Brian Wayland is an author at Incyte (United States) specializing in pharmacology, natural sciences, and drug discovery.

Top concepts

PharmacologyMedicineBiochemistryDrug DiscoveryNatural SciencesMedicinal ChemistryPharmacotherapyDrug DevelopmentOrganic ChemistryChemistry

Publications per year

2001–2019

10

Publications

10

INCB24360 (Epacadostat), a Highly Potent and Selective Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitor for Immuno-oncology

Eddy W. Yue, Richard Sparks, Padmaja Polam et al. · ACS Medicinal Chemistry Letters · 2017 · 290 citations · Full text

Discovery of Potent Competitive Inhibitors of Indoleamine 2,3-Dioxygenase with in Vivo Pharmacodynamic Activity and Efficacy in a Mouse Melanoma Model

Eddy W. Yue, Brent Douty, Brian Wayland et al. · Journal of Medicinal Chemistry · 2009 · 216 citations · Full text

Pharmacotherapy, Vivo Pharmacodynamic Activity, Pharmaceutical Chemistry +17

Structure-Based Design and Discovery of Protein Tyrosine Phosphatase Inhibitors Incorporating Novel Isothiazolidinone Heterocyclic Phosphotyrosine Mimetics

Andrew P. Combs, Eddy W. Yue, Michael J. Bower et al. · Journal of Medicinal Chemistry · 2005 · 101 citations · Full text

Molecular Docking, Crystal Structure, Medicinal Chemistry +13

Structural Basis for Inhibition of Protein-tyrosine Phosphatase 1B by Isothiazolidinone Heterocyclic Phosphonate Mimetics

J. Paul, Lucie Gonneville, Milton C. Hillman et al. · Journal of Biological Chemistry · 2006 · 83 citations · Full text

Structural Insights into the Design of Nonpeptidic Isothiazolidinone-containing Inhibitors of Protein-tyrosine Phosphatase 1B

J. Paul, Lucie Gonneville, Milton C. Hillman et al. · Journal of Biological Chemistry · 2006 · 60 citations · Full text

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