Brent Douty

INCB24360 (Epacadostat), a Highly Potent and Selective Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitor for Immuno-oncology

Eddy W. Yue, Richard Sparks, Padmaja Polam et al. · ACS Medicinal Chemistry Letters · 2017 · 290 citations · Full text

Discovery of Potent Competitive Inhibitors of Indoleamine 2,3-Dioxygenase with in Vivo Pharmacodynamic Activity and Efficacy in a Mouse Melanoma Model

Eddy W. Yue, Brent Douty, Brian Wayland et al. · Journal of Medicinal Chemistry · 2009 · 216 citations · Full text

Pharmacotherapy, Vivo Pharmacodynamic Activity, Pharmaceutical Chemistry +17

Structure-Based Design and Discovery of Protein Tyrosine Phosphatase Inhibitors Incorporating Novel Isothiazolidinone Heterocyclic Phosphotyrosine Mimetics

Andrew P. Combs, Eddy W. Yue, Michael J. Bower et al. · Journal of Medicinal Chemistry · 2005 · 101 citations · Full text

Molecular Docking, Crystal Structure, Medicinal Chemistry +13

Design of potent non-peptide competitive antagonists of the human bradykinin B2 receptor

Joseph M. Salvino, Peter R. Seoane, Brent Douty et al. · Journal of Medicinal Chemistry · 1993 · 96 citations · Full text

Peptide Engineering, Immunology, Altmetric Attention Score +21

The nonpeptide WIN 64338 is a bradykinin B2 receptor antagonist.

David G. Sawutz, Joseph M. Salvino, Roland E. Dolle et al. · Proceedings of the National Academy of Sciences · 1994 · 89 citations · Full text

Immunology, Peptide Science, Pharmacotherapy +19