Joseph M. Salvino

De novo design and synthesis of somatostatin non-peptide peptidomimetics utilizing .beta.-D-glucose as a novel scaffolding

Ralph Hirschmann, K. C. Nicolaou, Sherrie Pietranico et al. · Journal of the American Chemical Society · 1993 · 272 citations

Pharmacy, Biochemistry, Pharmacology +9

Nonpeptidal peptidomimetics with .beta.-D-glucose scaffolding. A partial somatostatin agonist bearing a close structural relationship to a potent, selective substance P antagonist

Ralph Hirschmann, K. C. Nicolaou, Sherrie Pietranico et al. · Journal of the American Chemical Society · 1992 · 222 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

Acetate acts as a metabolic immunomodulator by bolstering T-cell effector function and potentiating antitumor immunity in breast cancer

Katelyn D. Miller, Seamus O’Connor, Katherine Pniewski et al. · Nature Cancer · 2023 · 112 citations · Full text

Medicine, Immunology, Oncology +17

Targeted MDM2 Degradation Reveals a New Vulnerability for p53-Inactivated Triple-Negative Breast Cancer

Clare M. Adams, Ramkrishna Mitra, You‐Cai Xiao et al. · Cancer Discovery · 2023 · 107 citations · Full text

Medicine, Molecular Biology, Oncology +16

Novel safety-catch linker and its application with a Ugi/De-BOC/Cyclization (UDC) strategy to access carboxylic acids, 1,4-benzodiazepines, diketopiperazines, ketopiperazines and dihydroquinoxalinones

Christopher Hulme, John Peng, George Morton et al. · Tetrahedron Letters · 1998 · 104 citations

Pharmacy, Medicinal Chemistry, Pharmacology +8