Joseph M. Salvino

De novo design and synthesis of somatostatin non-peptide peptidomimetics utilizing .beta.-D-glucose as a novel scaffolding

Ralph Hirschmann, K. C. Nicolaou, Sherrie Pietranico et al. · Journal of the American Chemical Society · 1993 · 271 citations

Bioorganic Chemistry, Peptide Engineering, Somatostatin Non-peptide Peptidomimetics +19

Nonpeptidal peptidomimetics with .beta.-D-glucose scaffolding. A partial somatostatin agonist bearing a close structural relationship to a potent, selective substance P antagonist

Ralph Hirschmann, K. C. Nicolaou, Sherrie Pietranico et al. · Journal of the American Chemical Society · 1992 · 222 citations

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +15

Novel safety-catch linker and its application with a Ugi/De-BOC/Cyclization (UDC) strategy to access carboxylic acids, 1,4-benzodiazepines, diketopiperazines, ketopiperazines and dihydroquinoxalinones

Christopher Hulme, John Peng, George Morton et al. · Tetrahedron Letters · 1998 · 104 citations

Medicine, Drug Discovery, Novel Safety-catch Linker +5

Acetate acts as a metabolic immunomodulator by bolstering T-cell effector function and potentiating antitumor immunity in breast cancer

Katelyn D. Miller, Seamus O’Connor, Katherine Pniewski et al. · Nature Cancer · 2023 · 104 citations · Full text

Breast Oncology, Cancer Immunosurveillance, Medicine +9

Design of potent non-peptide competitive antagonists of the human bradykinin B2 receptor

Joseph M. Salvino, Peter R. Seoane, Brent Douty et al. · Journal of Medicinal Chemistry · 1993 · 96 citations · Full text

Peptide Engineering, Immunology, Altmetric Attention Score +21