K. C. Nicolaou

Chemistry and Biology of the Enediyne Anticancer Antibiotics

K. C. Nicolaou, Wei‐Min Dai · Angewandte Chemie International Edition in English · 1991 · 982 citations

Combinatorial Chemistry, Bioorganic Chemistry, Family Members +16

A common pharmacophore for epothilone and taxanes: Molecular basis for drug resistance conferred by tubulin mutations in human cancer cells

Paraskevi Giannakakou, Rick Gussio, Eva Nogales et al. · Proceedings of the National Academy of Sciences · 2000 · 475 citations

Tubulin Binding, Drug Target, Molecular Biology +19

Protracted low-dose effects on human endothelial cell proliferation and survival in vitro reveal a selective antiangiogenic window for various chemotherapeutic drugs.

Guido Bocci, K. C. Nicolaou, Robert S. Kerbel · PubMed · 2002 · 445 citations

Various Chemotherapeutic Drugs, Endothelial Cells, Immunology +19

A Chemical, Genetic, and Structural Analysis of the Nuclear Bile Acid Receptor FXR

Michael Downes, Mark A. Verdecia, Anthony J. Roecker et al. · Molecular Cell · 2003 · 379 citations · Full text

Biochemistry, Biliary Tract, Natural Sciences +7

Practical synthesis of oligosaccharides. Partial synthesis of avermectin B1a

K. C. Nicolaou, Roland E. Dolle, Demetris P. Papahatjis · Journal of the American Chemical Society · 1984 · 311 citations

Bioorganic Chemistry, Partial Synthesis, Biochemistry +10