Concepedia

Rick Gussio

RG

Statistics

Publications

59

Citations

4.2K

H-Index

35

Active since

1989

Affiliations

National Cancer Institute(Current)

Science Applications International Corporation (United States)

Frederick National Laboratory for Cancer Research

United States Army Medical Research Institute of Infectious Diseases

University of Pittsburgh

Rick Gussio is an author at National Cancer Institute specializing in pharmacology, medicinal chemistry, and drug discovery.

Publications per year

1989–2019

59

Publications

59

A common pharmacophore for epothilone and taxanes: Molecular basis for drug resistance conferred by tubulin mutations in human cancer cells

Paraskevi Giannakakou, Rick Gussio, Eva Nogales et al. · Proceedings of the National Academy of Sciences · 2000 · 477 citations

, , +15

Paullones are potent inhibitors of glycogen synthase kinase‐3β and cyclin‐dependent kinase 5/p25

Maryse Leost, Christiane Schultz, Andreas Link et al. · European Journal of Biochemistry · 2000 · 373 citations · Full text

, , +16

Paullones, a Series of Cyclin-Dependent Kinase Inhibitors:  Synthesis, Evaluation of CDK1/Cyclin B Inhibition, and in Vitro Antitumor Activity

Christiane Schultz, Andreas Link, Maryse Leost et al. · Journal of Medicinal Chemistry · 1999 · 330 citations · Full text

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A Common Pharmacophore for a Diverse Set of Colchicine Site Inhibitors Using a Structure-Based Approach

Tam Luong Nguyen, Connor F. McGrath, Ann Hermone et al. · Journal of Medicinal Chemistry · 2005 · 287 citations

, , +17

Discovery and initial characterization of the paullones, a novel class of small-molecule inhibitors of cyclin-dependent kinases.

Daniel Zaharevitz, Rick Gussio, Maryse Leost et al. · PubMed · 1999 · 226 citations

, , +15

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