Daniel Zaharevitz

An Information-Intensive Approach to the Molecular Pharmacology of Cancer

John N. Weinstein, Timothy G. Myers, P M O'Connor et al. · Science · 1997 · 1.2K citations

Medicine, Oncology, Pharmacology +14

Relationships between drug activity in NCI preclinical in vitro and in vivo models and early clinical trials

J I Johnson, Shannon Decker, Daniel Zaharevitz et al. · British Journal of Cancer · 2001 · 858 citations · Full text

Medicine, Oncology, Pharmacology +14

A common pharmacophore for epothilone and taxanes: Molecular basis for drug resistance conferred by tubulin mutations in human cancer cells

Paraskevi Giannakakou, Rick Gussio, Eva Nogales et al. · Proceedings of the National Academy of Sciences · 2000 · 477 citations

Medicine, Medicinal Chemistry, Pharmacology +15

Paullones are potent inhibitors of glycogen synthase kinase‐3β and cyclin‐dependent kinase 5/p25

Maryse Leost, Christiane Schultz, Andreas Link et al. · European Journal of Biochemistry · 2000 · 373 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Paullones, a Series of Cyclin-Dependent Kinase Inhibitors:  Synthesis, Evaluation of CDK1/Cyclin B Inhibition, and in Vitro Antitumor Activity

Christiane Schultz, Andreas Link, Maryse Leost et al. · Journal of Medicinal Chemistry · 1999 · 330 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16