Maryse Leost

GSK-3-Selective Inhibitors Derived from Tyrian Purple Indirubins

Laurent Meijer, Alexios-Leandros Skaltsounis, Prokopios Magiatis et al. · Chemistry & Biology · 2003 · 815 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases

Ralph Hoessel, Sophie Leclerc, Jane Endicott et al. · Nature Cell Biology · 1999 · 814 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Structural Basis for the Synthesis of Indirubins as Potent and Selective Inhibitors of Glycogen Synthase Kinase-3 and Cyclin-Dependent Kinases

Panagiotis Polychronopoulos, Prokopios Magiatis, Alexios‐Léandros Skaltsounis et al. · Journal of Medicinal Chemistry · 2004 · 376 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Paullones, a Series of Cyclin-Dependent Kinase Inhibitors:  Synthesis, Evaluation of CDK1/Cyclin B Inhibition, and in Vitro Antitumor Activity

Christiane Schultz, Andreas Link, Maryse Leost et al. · Journal of Medicinal Chemistry · 1999 · 330 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors

Young‐Tae Chang, Nathanael S. Gray, Gustavo R. Rosania et al. · Chemistry & Biology · 1999 · 267 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +14