Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells

The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells

Ivaylo I. Ivanov, Brent S. McKenzie, Liang Zhou et al. · Cell · 2006 · 5.1K citations · Full text

Life Sciences, Cell Biology, Immunology +16

Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides

Spencer C. Liang, Xiangyang Tan, Deborah Luxenberg et al. · The Journal of Experimental Medicine · 2006 · 2.3K citations · Full text

Life Sciences, Immunology, Microbiology +17

Development, cytokine profile and function of human interleukin 17–producing helper T cells

Nicholas J. Wilson, Katia Boniface, Jason R. Chan et al. · Nature Immunology · 2007 · 2K citations

Life Sciences, Cell Biology, Immunology +14

Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

Yan Zheng, Dimitry M. Danilenko, Patricia Valdez et al. · Nature · 2006 · 1.8K citations

Life Sciences, Immunology, Pathology +14

Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

Francisco J. Quintana, Alexandre S. Basso, Antonio Iglesias et al. · Nature · 2008 · 1.8K citations

Life Sciences, Immunology, Molecular Biology +14