Concepedia

Th2 Immune Response

Th2 Immune Response is a CD4+ T helper cell-mediated adaptive immune response characterized by the secretion of interleukin-4, interleukin-5, and interleukin-13, which drives B cell class switching to IgE production and is predominantly involved in the pathogenesis of IgE-mediated allergic reactions and type I hypersensitivity.

8.3K

Publications

656.2K

Citations

39.3K

Authors

5K

Institutions

Publications per year

2017–2026

1.4K

Variants

Th2 Response

Parents

Publications

8.3K

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

Timothy R. Mosmann, Holly Cherwinski, M W Bond et al. · The Journal of Immunology · 1986 · 7.5K citations

, , +16

Predominant T<sub>H2</sub>-like Bronchoalveolar T-Lymphocyte Population in Atopic Asthma

Douglas S. Robinson, Qutayba Hamid, Sun Ying et al. · New England Journal of Medicine · 1992 · 2.8K citations

, , +17

Interleukin-13: Central Mediator of Allergic Asthma

Marsha Wills‐Karp, Jackie Luyimbazi, Xueying Xu et al. · Science · 1998 · 2.6K citations

, , +16

The Transcription Factor GATA-3 Is Necessary and Sufficient for Th2 Cytokine Gene Expression in CD4 T Cells

Wei-ping Zheng, Richard A. Flavell · Cell · 1997 · 2.4K citations · Full text

, , +17

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

Daniel R. Neill, See Heng Wong, Agustin Bellosi et al. · Nature · 2010 · 2K citations · Full text

, , +14

1–5 of 8.3K

Authors

39.3K

  1. AN
    Andrew N. J. McKenzie

    MRC Laboratory of Molecular Biology, United Kingdom

    49 publications · 11.1K citations

    41

    h-index

  2. TA
    Thomas A. Wynn

    National Institute of Allergy and Infectious Diseases, United States

    35 publications · 4.7K citations

    34

    h-index

  3. JF
    Joseph F. Urban

    Beltsville Human Nutrition Research Center, United States

    41 publications · 4.6K citations

    33

    h-index

  4. EJ
    Edward J. Pearce

    Max Planck Institute of Immunobiology and Epigenetics, Germany

    37 publications · 5.7K citations

    31

    h-index

  5. FB
    Frank Brombacher

    University of Cape Town, South Africa

    42 publications · 3.5K citations

    30

    h-index

1–5 of 39.3K

Institutions

5K

  1. Harvard University

    Cambridge, United States

    97 h-index

    914 publications

    118.4K citations

  2. National Institutes of Health

    Bethesda, United States

    86 h-index

    700 publications

    84.2K citations

  3. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    79 h-index

    521 publications

    76.5K citations

  4. Brigham and Women's Hospital

    Boston, United States

    72 h-index

    574 publications

    78.7K citations

  5. Inserm

    Paris, France

    65 h-index

    800 publications

    61.4K citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    63 h-index

    211 publications

    51.8K citations

  7. Yale University

    New Haven, United States

    61 h-index

    364 publications

    72.2K citations

  8. University of Pennsylvania

    Philadelphia, United States

    54 h-index

    337 publications

    36.1K citations

1–8 of 5K

Venues

  1. The Journal of Immunology

    JI · 1.3K publications · 149.1K citations

    184

    h-index

  2. The Journal of Experimental Medicine

    212 publications · 56.7K citations

    129

    h-index

  3. Journal of Clinical Investigation

    JCI · 122 publications · 24.9K citations

    88

    h-index

  4. European Journal of Immunology

    EJI · 323 publications · 22.9K citations

    85

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 101 publications · 17.3K citations

    72

    h-index

1–5