Edward J. Pearce

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression

Chih‐Hao Chang, Jing Qiu, David O’Sullivan et al. · Cell · 2015 · 3.1K citations · Full text

Tumor Biology, Oncology, Medicine +11

Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis

Chih‐Hao Chang, Jonathan D. Curtis, Leonard B. Maggi et al. · Cell · 2013 · 2.1K citations · Full text

Signal Transduction, Aerobic Glycolysis, Cell Signaling +8

Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization

Abhishek Jha, Stanley Ching‐Cheng Huang, Alexey Sergushichev et al. · Immunity · 2015 · 1.9K citations · Full text

Transcriptional Regulation, Systems Biology, Functional Genomics +15

Mitochondrial Respiratory Capacity Is a Critical Regulator of CD8+ T Cell Memory Development

Gerritje J. W. van der Windt, Bart Everts, Chih‐Hao Chang et al. · Immunity · 2011 · 1.5K citations · Full text

Immunological Memory, Mitochondrial Function, Organelle Dynamic +10

Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation

Vicky Lampropoulou, Alexey Sergushichev, Monika Bambousková et al. · Cell Metabolism · 2016 · 1.4K citations · Full text

Inflammation, Succinate Dehydrogenase, Macrophage Metabolic Remodeling +12