Concepedia

Hypoxia-Induced Energy Stress Regulates mRNA Translation and Cell Growth

Liping Liu, Timothy P. Cash, Russell G. Jones, Brian Keith, Craig B. Thompson, M. Celeste Simon

Molecular Cell · 2006 · 609 citations · 27 references

DOIFull text

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Concepts

References

27

TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival

Ken Inoki, Tianqing Zhu, Kun‐Liang Guan · Cell · 2003 · 3.9K citations · Full text

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Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

Heather P. Harding, Yuhong Zhang, David Ron · Nature · 1999 · 3.3K citations

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TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

Ken Inoki, Yong Li, Tianquan Zhu et al. · Nature Cell Biology · 2002 · 3.1K citations

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AMP-Activated Protein Kinase Induces a p53-Dependent Metabolic Checkpoint

Russell G. Jones, David R. Plas, Sara Kubek et al. · Molecular Cell · 2005 · 1.6K citations · Full text

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Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

James Brugarolas, Kui Lei, Rebecca L. Hurley et al. · Genes & Development · 2004 · 1.4K citations · Full text

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