Concepedia

Translation Regulation

Translation Regulation is a post-transcriptional gene regulatory process that controls the rate, timing, and specificity of protein synthesis from mRNAs by modulating ribosome recruitment and activity—primarily at initiation but also during elongation and termination—through cis-acting RNA elements and trans-acting factors in response to cellular and environmental signals.

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Genetic regulatory mechanisms in the synthesis of proteins

François Jacob, Jacques Monod · Journal of Molecular Biology · 1961 · 6.6K citations

, , +12

Alternative isoform regulation in human tissue transcriptomes

Eric T. Wang, Rickard Sandberg, Shujun Luo et al. · Nature · 2008 · 5.4K citations · Full text

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Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

Marilyn Kozak · Cell · 1986 · 4.9K citations

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A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

Gray D. Shaw, Robert Kamen · Cell · 1986 · 4.1K citations

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Human MicroRNA Targets

Bino John, Anton J. Enright, Alexei A. Aravin et al. · PLoS Biology · 2004 · 3.9K citations · Full text

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  1. NS
    Nahum Sonenberg

    McGill University, Canada

    226 publications · 38.9K citations

    110

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  2. AG
    Alan G. Hinnebusch

    Eunice Kennedy Shriver National Institute of Child Health and Human Development, United States

    117 publications · 11.1K citations

    62

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  3. MW
    Matthias W. Hentze

    European Molecular Biology Laboratory, Germany

    76 publications · 11.8K citations

    59

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  4. JW
    John W.B. Hershey

    University of California, Davis, United States

    75 publications · 7.8K citations

    51

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  5. MG
    Myriam Gorospe

    National Institute on Aging, United States

    67 publications · 7.7K citations

    50

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  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    183 h-index

    1.4K publications

    359.8K citations

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    Cambridge, United States

    133 h-index

    1.5K publications

    231.6K citations

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    Montreal, Canada

    124 h-index

    1.4K publications

    194.1K citations

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    Paris, France

    110 h-index

    2.8K publications

    217.2K citations

  5. National Institutes of Health

    Bethesda, United States

    109 h-index

    1.4K publications

    142.2K citations

  6. Massachusetts Institute of Technology

    Cambridge, United States

    99 h-index

    667 publications

    113.1K citations

  7. Stanford University

    Stanford, United States

    89 h-index

    798 publications

    100.8K citations

  8. University of California, Berkeley

    Berkeley, United States

    87 h-index

    533 publications

    71.5K citations

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  3. Cell

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  4. Journal of Biological Chemistry

    JBC · 1.4K publications · 108.7K citations

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  5. The EMBO Journal

    350 publications · 54.2K citations

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