James Brugarolas

Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

James Brugarolas, Kui Lei, Rebecca L. Hurley et al. · Genes & Development · 2004 · 1.4K citations · Full text

Radiation-induced cell cycle arrest compromised by p21 deficiency

James Brugarolas, Chitra Chandrasekaran, Jeffrey I. Gordon et al. · Nature · 1995 · 1.2K citations

Radiation Oncology, Cell Division, Radiation Effect +5

BAP1 loss defines a new class of renal cell carcinoma

Samuel Peña‐Llopis, Silvia Vega-Rubín-de-Celis, Arnold Liao et al. · Nature Genetics · 2012 · 973 citations · Full text

mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways

Pradip K. Majumder, Phillip G. Febbo, Rachel Bikoff et al. · Nature Medicine · 2004 · 954 citations

Urology, Genitourinary Cancer, Hif-1-dependent Pathways +7

Targeting renal cell carcinoma with a HIF-2 antagonist

Wenfang Chen, Haley Hill, Alana Christie et al. · Nature · 2016 · 697 citations · Full text

Urology, Genitourinary Cancer, Renal Cell Carcinoma +4