Concepedia

Translational Regulation

Translational Regulation is a mode of gene expression regulation that controls the rate, efficiency, and specificity of protein synthesis by modulating the translation of mRNA into polypeptides, chiefly via mechanisms affecting ribosome recruitment and activity during initiation, elongation, and termination.

16.9K

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1.3M

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55.2K

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5.2K

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2017–2026

3.2K

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16.9K

Alternative isoform regulation in human tissue transcriptomes

Eric T. Wang, Rickard Sandberg, Shujun Luo et al. · Nature · 2008 · 5.4K citations · Full text

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Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

Marilyn Kozak · Cell · 1986 · 4.9K citations

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A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

Gray D. Shaw, Robert Kamen · Cell · 1986 · 4.1K citations

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Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling

Nicholas T. Ingolia, Sina Ghaemmaghami, J. Robert Newman et al. · Science · 2009 · 4.1K citations · Full text

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XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription Factor

Hiderou Yoshida, Toshie Matsui, Akira Yamamoto et al. · Cell · 2001 · 4.1K citations · Full text

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1–5 of 16.9K

Authors

55.2K

  1. NS
    Nahum Sonenberg

    McGill University, Canada

    212 publications · 35.8K citations

    104

    h-index

  2. AG
    Alan G. Hinnebusch

    Eunice Kennedy Shriver National Institute of Child Health and Human Development, United States

    101 publications · 9.2K citations

    55

    h-index

  3. SR
    Scot R. Kimball

    Pennsylvania State University, United States

    84 publications · 7.9K citations

    51

    h-index

  4. JD
    Joel D. Richter

    University of Massachusetts Chan Medical School, United States

    70 publications · 8.1K citations

    50

    h-index

  5. MW
    Matthias W. Hentze

    European Molecular Biology Laboratory, Germany

    66 publications · 9.4K citations

    49

    h-index

1–5 of 55.2K

Institutions

5.2K

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    171 h-index

    1.2K publications

    321.4K citations

  2. Harvard University

    Cambridge, United States

    131 h-index

    1.4K publications

    227.4K citations

  3. McGill University

    Montreal, Canada

    118 h-index

    1.3K publications

    171.9K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    106 h-index

    2.6K publications

    196.5K citations

  5. National Institutes of Health

    Bethesda, United States

    105 h-index

    1.3K publications

    144.6K citations

  6. Massachusetts Institute of Technology

    Cambridge, United States

    100 h-index

    637 publications

    127K citations

  7. Johns Hopkins University

    Baltimore, United States

    90 h-index

    686 publications

    84.1K citations

  8. Stanford University

    Stanford, United States

    89 h-index

    809 publications

    93.6K citations

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Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 965 publications · 112.8K citations

    172

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  2. Journal of Biological Chemistry

    JBC · 1.4K publications · 105.7K citations

    146

    h-index

  3. Cell

    223 publications · 81.5K citations

    144

    h-index

  4. Molecular and Cellular Biology

    MCB · 792 publications · 72.9K citations

    140

    h-index

  5. Nucleic Acids Research

    1.1K publications · 69K citations

    123

    h-index

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