Time to knit · 2000 · 14 citations · 8 references
Life SciencesBioengineeringBiotechnologyBiochemical EngineeringBioprocess EngineeringIndustrial BiotechnologyBioprocess OptimizationEnzyme ProductionFermentation KineticsIndustrial FermentationMicrobial Enzyme ProductionMicrobial FermentationEnzyme Production OptimizationFermentation Media OptimizationFermentation OptimizationFermentation Process OptimizationOptimal Experimental DesignsPlackett-burman DesignsPolygalacturonase ActivitySubstrate Optimization
Statistically based experimental designs were applied for endopolygalacturonase production by mutated strains of Aspergillus niger using apple pomace waste in solid-state fermentation (SSF). The Plackett-Burman design was used to search for the main factors. Urea was found to be the most significant factor (p<0.05) among these variables. To study the mutual interactions between variables and find the optimum medium, Doehlert design was performed to investigate the effect of the medium compone
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