Concepedia

TFE3 transcriptionally activates hepatic IRS-2, participates in insulin signaling and ameliorates diabetes

Yoshimi Nakagawa, Hitoshi Shimano, Tomohiro Yoshikawa, Tomohiro Ide, Mariko Tamura, Mika Furusawa, Takashi Yamamoto, Noriyuki Inoue, Takashi Matsuzaka, Akimitsu Takahashi,

Nature Medicine · 2005 · 208 citations · 32 references

DOI

Concepts

References

32

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

Jay D. Horton, Joseph L. Goldstein, Michael S. Brown · Journal of Clinical Investigation · 2002 · 4K citations · Full text

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A simplified system for generating recombinant adenoviruses

Tong‐Chuan He, Shibin Zhou, Luís Teixeira da Costa et al. · Proceedings of the National Academy of Sciences · 1998 · 3.2K citations

, , +15

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

John C. Yoon, Pere Puigserver, Guoxun Chen et al. · Nature · 2001 · 1.8K citations

, , +14

Disruption of IRS-2 causes type 2 diabetes in mice

Dominic J. Withers, Julio Sanchez Gutierrez, Heather Towery et al. · Nature · 1998 · 1.8K citations

, , +12

Insulin-regulated hepatic gluconeogenesis through FOXO1–PGC-1α interaction

Pere Puigserver, James Rhee, Jerry Donovan et al. · Nature · 2003 · 1.5K citations

, , +14