Dominic J. Withers

Disruption of IRS-2 causes type 2 diabetes in mice

Dominic J. Withers, Julio Sanchez Gutierrez, Heather Towery et al. · Nature · 1998 · 1.8K citations

Metabolic Syndrome, Medicine, Diabetes +5

Inhibition of Food Intake in Obese Subjects by Peptide YY_3–36

Rachel L. Batterham, Mark A. Cohen, Carel W. le Roux et al. · New England Journal of Medicine · 2003 · 1.6K citations

Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span

Colin Selman, Jennifer M. A. Tullet, Daniela Wieser et al. · Science · 2009 · 1.1K citations

Anti-aging, Molecular Regulation, Cell Death +22

Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation

B. Nave, D. Margriet Ouwens, Dominic J. Withers et al. · Biochemical Journal · 1999 · 918 citations · Full text

Convergence Point, Protein Translation, Insulin Signaling +17

Longer lifespan, altered metabolism, and stress resistance in <i>Drosophila</i> from ablation of cells making insulin-like ligands

Susan Broughton, Matthew D. W. Piper, Tomoatsu Ikeya et al. · Proceedings of the National Academy of Sciences · 2005 · 828 citations · Full text

Stress Resistance, Drosophila Insulin-like Peptides, Longer Lifespan +19