Concepedia

Versatile templates for the development of novel kinase inhibitors: Discovery of novel CDK inhibitors

Michael P. Dwyer, Kamil Paruch, Carmen Álvarez, Ronald J. Doll, Kerry Keertikar, José S. Duca, Thierry Fischmann, Alan Hruza, Vincent Madison, Emma Lees,

Bioorganic & Medicinal Chemistry Letters · 2007 · 39 citations · 16 references

DOI

Concepts

References

16

The Pezcoller lecture: cancer cell cycles revisited.

C J Sherr · PubMed · 2000 · 1.2K citations

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Discovery of a Potent and Selective Inhibitor of Cyclin-Dependent Kinase 4/6

Peter L. Toogood, Patricia J. Harvey, Joseph T. Repine et al. · Journal of Medicinal Chemistry · 2005 · 503 citations · Full text

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<i>In vitro</i> and <i>in vivo</i> antitumor properties of the cyclin dependent kinase inhibitor CYC202 (R‐roscovitine)

Steven J. McClue, David Blake, Rosemary G. Clarke et al. · International Journal of Cancer · 2002 · 363 citations · Full text

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<i>N</i>-(Cycloalkylamino)acyl-2-aminothiazole Inhibitors of Cyclin-Dependent Kinase 2. <i>N</i>-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4- piperidinecarboxamide (BMS-387032), a Highly Efficacious and Selective Antitumor Agent

Raj N. Misra, Hai‐Yun Xiao, Kyoung S. Kim et al. · Journal of Medicinal Chemistry · 2004 · 251 citations · Full text

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Synthesis and antischistosomal activity of certain pyrazolo[1,5-a]pyrimidines

K. SENGA, Thomas Novinson, H.R. WILSON et al. · Journal of Medicinal Chemistry · 1981 · 146 citations

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