Hai‐Yun Xiao

<i>N</i>-(Cycloalkylamino)acyl-2-aminothiazole Inhibitors of Cyclin-Dependent Kinase 2. <i>N</i>-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4- piperidinecarboxamide (BMS-387032), a Highly Efficacious and Selective Antitumor Agent

Raj N. Misra, Hai‐Yun Xiao, Kyoung S. Kim et al. · Journal of Medicinal Chemistry · 2004 · 251 citations · Full text

Chemoprevention Strategy, Immunology, Pharmacotherapy +19

Synthesis and biological activity of N-aryl-2-aminothiazoles: potent pan inhibitors of cyclin-dependent kinases

Raj N. Misra, Hai‐Yun Xiao, David Williams et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 56 citations · Full text

Biological Activity, Cyclin-dependent Kinases, Biochemistry +10

Identification of a novel series of tetrahydrodibenzazocines as inhibitors of 17β-hydroxysteroid dehydrogenase type 3

Brian E. Fink, Ashvinikumar V. Gavai, John S. Tokarski et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 40 citations · Full text

Medicinal Chemistry, Aldehyde Dehydrogenase, Novel Series +7

Biologic-like In Vivo Efficacy with Small Molecule Inhibitors of TNFα Identified Using Scaffold Hopping and Structure-Based Drug Design Approaches

Hai‐Yun Xiao, Ning Li, James J.‐W. Duan et al. · Journal of Medicinal Chemistry · 2020 · 39 citations · Full text

Identification and Preclinical Pharmacology of BMS-986104: A Differentiated S1P₁ Receptor Modulator in Clinical Trials

T. G. Murali Dhar, Hai‐Yun Xiao, Jenny Xie et al. · ACS Medicinal Chemistry Letters · 2016 · 31 citations · Full text

Immunology, Pharmacotherapy, Clinical Validation +19