Peter L. Toogood

Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts

David W. Fry, Patricia J. Harvey, Paul R. Keller et al. · Molecular Cancer Therapeutics · 2004 · 1.2K citations

Discovery of a Potent and Selective Inhibitor of Cyclin-Dependent Kinase 4/6

Peter L. Toogood, Patricia J. Harvey, Joseph T. Repine et al. · Journal of Medicinal Chemistry · 2005 · 498 citations · Full text

Drug Target, Exquisite Selectivity, Pharmacotherapy +19

Sterol metabolism controls TH17 differentiation by generating endogenous RORγ agonists

Xiao Hu, Yahong Wang, Ling-Yang Hao et al. · Nature Chemical Biology · 2015 · 225 citations

Metabolic Syndrome, Oxysterol, Medicine +9

A Novel Orally Active Small Molecule Potently Induces G1 Arrest in Primary Myeloma Cells and Prevents Tumor Growth by Specific Inhibition of Cyclin-Dependent Kinase 4/6

Linda B. Baughn, Maurizio Di Liberto, Kaida Wu et al. · Cancer Research · 2006 · 222 citations · Full text

Synthesis of (−)-PNU-286607 by Asymmetric Cyclization of Alkylidene Barbiturates

J. Craig Ruble, Alexander R. Hurd, Timothy A. Johnson et al. · Journal of the American Chemical Society · 2009 · 162 citations

Combinatorial Chemistry, Bioorganic Chemistry, Organic Chemistry +17