Concepedia

Cdk Activation

CDK Activation is the regulated phosphorylation event that confers enzymatic activity to cyclin-dependent kinases, enabling their role in driving cell-cycle progression through specific substrate phosphorylation.

1.7K

Publications

151.7K

Citations

8.3K

Authors

1.6K

Institutions

Publications per year

2017–2026

204

Parents

Publications

1.7K

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest.

Kornélia Polyák, Jun‐ya Kato, Michael J. Solomon et al. · Genes & Development · 1994 · 2K citations · Full text

, , +17

Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2

Jenő Gyuris · Cell · 1993 · 1.5K citations

, , +11

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

René H. Medema, Geert J.P.L. Kops, Johannes L. Bos et al. · Nature · 2000 · 1.4K citations

, , +14

Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

Philip D. Jeffrey, Alicia A. Russo, Kornélia Polyák et al. · Nature · 1995 · 1.4K citations

, , +9

Conservation of the Chk1 Checkpoint Pathway in Mammals: Linkage of DNA Damage to Cdk Regulation Through Cdc25

Yolanda Sánchez, Calvin Wong, Richard S. Thoma et al. · Science · 1997 · 1.3K citations

, , +17

1–5 of 1.7K

Authors

8.3K

  1. PK
    Philipp Kaldis

    Institute of Molecular and Cell Biology, Singapore

    19 publications · 1.3K citations

    18

    h-index

  2. RP
    Robert P. Fisher

    Icahn School of Medicine at Mount Sinai, United States

    17 publications · 2.6K citations

    17

    h-index

  3. MJ
    Mark J. Solomon

    Yale University, United States

    15 publications · 728 citations

    14

    h-index

  4. DO
    David O. Morgan

    University of California, San Francisco, United States

    14 publications · 4.7K citations

    14

    h-index

  5. MU
    Masaaki Umeda

    Nara Institute of Science and Technology, Japan

    14 publications · 833 citations

    13

    h-index

1–5 of 8.3K

Institutions

1.6K

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    52 h-index

    178 publications

    53.7K citations

  2. Harvard University

    Cambridge, United States

    51 h-index

    284 publications

    49.8K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    43 h-index

    264 publications

    32.4K citations

  4. University of California, San Francisco

    San Francisco, United States

    35 h-index

    119 publications

    23.5K citations

  5. Inserm

    Paris, France

    26 h-index

    127 publications

    9.5K citations

  6. Yale University

    New Haven, United States

    24 h-index

    77 publications

    6.6K citations

  7. Memorial Sloan Kettering Cancer Center

    New York, United States

    24 h-index

    72 publications

    35.9K citations

  8. The University of Tokyo

    Tokyo, Japan

    23 h-index

    137 publications

    7.1K citations

1–8 of 1.6K

Venues

  1. Journal of Biological Chemistry

    JBC · 127 publications · 11K citations

    61

    h-index

  2. Oncogene

    79 publications · 6.5K citations

    50

    h-index

  3. The EMBO Journal

    52 publications · 9.4K citations

    44

    h-index

  4. Molecular and Cellular Biology

    MCB · 61 publications · 6.9K citations

    44

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 47 publications · 5.1K citations

    40

    h-index

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