Concepedia

Centrosome-associated Chk1 prevents premature activation of cyclin-B–Cdk1 kinase

Alwin Krämer, Niels Mailand, Claudia Lukas, Randi G. Syljuåsen, Christopher J. Wilkinson, Erich A. Nigg, Jiří Bártek

Nature Cell Biology · 2004 · 338 citations · 31 references

DOI

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References

31

Chk1 is an essential kinase that is regulated by Atr and required for the G<sub>2</sub>/M DNA damage checkpoint

Qinghua Liu, Saritha Guntuku, Xian-Shu Cui et al. · Genes & Development · 2000 · 1.6K citations · Full text

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Proteomic characterization of the human centrosome by protein correlation profiling

Jens Andersen, Christopher J. Wilkinson, Thibault Mayor et al. · Nature · 2003 · 1.3K citations

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Conservation of the Chk1 Checkpoint Pathway in Mammals: Linkage of DNA Damage to Cdk Regulation Through Cdc25

Yolanda Sánchez, Calvin Wong, Richard S. Thoma et al. · Science · 1997 · 1.3K citations

, , +17

Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo

Anne Blangy, Heidi A. Lane, Pierre d'Hérin et al. · Cell · 1995 · 963 citations · Full text

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Rapid Destruction of Human Cdc25A in Response to DNA Damage

Niels Mailand, Jacob Falck, Claudia Lukas et al. · Science · 2000 · 770 citations

, , +17