Concepedia

Cyclin B-cdk1 Complex

The Cyclin B-Cdk1 Complex is a heterodimeric serine/threonine protein kinase composed of cyclin B and cyclin-dependent kinase 1 that regulates the G2 to M phase transition of the cell cycle by phosphorylating key substrates involved in nuclear envelope breakdown, chromosome condensation, and spindle assembly.

405

Publications

34.1K

Citations

2.1K

Authors

630

Institutions

Publications per year

2017–2026

71

Variants

Maturation-promoting FactorMpf

Parents

Publications

405

Cdk1 is sufficient to drive the mammalian cell cycle

David Santamarı́a, Cédric Barrière, Antonio Cerqueira et al. · Nature · 2007 · 1.1K citations

, , +12

A family of human cdc2‐related protein kinases.

Matthew Meyerson, G H Enders, Chia‐Ling Wu et al. · The EMBO Journal · 1992 · 921 citations · Full text

, , +8

Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity

Julian He, S Choe, Robert Walker et al. · Journal of Virology · 1995 · 918 citations · Full text

, , +14

The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae

Étienne Schwob · Cell · 1994 · 893 citations

, , +14

Progressive Activation of CyclinB1-Cdk1 Coordinates Entry to Mitosis

Olivier Gavet, Jonathon Pines · Developmental Cell · 2010 · 858 citations · Full text

, , +13

1–5 of 405

Authors

2.1K

  1. JP
    Jonathon Pines

    The Gurdon Institute, United Kingdom

    9 publications · 2.5K citations

    9

    h-index

  2. LM
    Laurent Meijer

    Station Biologique de Roscoff, France

    7 publications · 1.3K citations

    7

    h-index

  3. TK
    Takeo Kishimoto

    Tokyo Institute of Technology, Japan

    6 publications · 154 citations

    6

    h-index

  4. JL
    Jean‐Claude Labbé

    Centre National de la Recherche Scientifique, France

    5 publications · 347 citations

    5

    h-index

  5. AC
    Anna Castro

    Centre de Recherche en Biologie cellulaire de Montpellier, France

    5 publications · 269 citations

    5

    h-index

1–5 of 2.1K

Institutions

630

  1. Centre National de la Recherche Scientifique

    Paris, France

    22 h-index

    143 publications

    13K citations

  2. Inserm

    Paris, France

    12 h-index

    42 publications

    2.2K citations

  3. Newcastle University

    Newcastle upon Tyne, United Kingdom

    8 h-index

    30 publications

    2.5K citations

  4. Harvard University

    Cambridge, United States

    8 h-index

    14 publications

    1.7K citations

  5. University of California San Diego

    San Diego, United States

    8 h-index

    16 publications

    1.7K citations

  6. Station Biologique de Roscoff

    Roscoff, France

    8 h-index

    25 publications

    2.2K citations

  7. Max Planck Institute of Biochemistry

    Martinsried, Germany

    7 h-index

    21 publications

    2.7K citations

  8. Heidelberg University

    Heidelberg, Germany

    7 h-index

    21 publications

    1.4K citations

1–8 of 630

Venues

  1. Journal of Biological Chemistry

    JBC · 30 publications · 2.3K citations

    24

    h-index

  2. The Journal of Cell Biology

    JCB · 20 publications · 1.8K citations

    18

    h-index

  3. Molecular Biology of the Cell

    MBC · 16 publications · 1.8K citations

    16

    h-index

  4. Cell Cycle

    20 publications · 800 citations

    15

    h-index

  5. PLoS ONE

    16 publications · 749 citations

    13

    h-index

1–5