David Santamarı́a

Cdk1 is sufficient to drive the mammalian cell cycle

David Santamarı́a, Cédric Barrière, Antonio Cerqueira et al. · Nature · 2007 · 1.1K citations

Life Sciences, Cell Biology, Molecular Biology +12

Mammalian Cells Cycle without the D-Type Cyclin-Dependent Kinases Cdk4 and Cdk6

Marcos Malumbres, Rocı́o Sotillo, David Santamarı́a et al. · Cell · 2004 · 788 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

A Synthetic Lethal Interaction between K-Ras Oncogenes and Cdk4 Unveils a Therapeutic Strategy for Non-small Cell Lung Carcinoma

Marta Puyol, Alberto Martín, Pierre Dubus et al. · Cancer Cell · 2010 · 412 citations · Full text

Medicine, Cancer Biology, Oncology +17

Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy

Matthew Holderfield, Bianca J. Lee, Jingjing Jiang et al. · Nature · 2024 · 318 citations · Full text

Medicine, Oncology, Pharmacology +16

c-Raf, but Not B-Raf, Is Essential for Development of K-Ras Oncogene-Driven Non-Small Cell Lung Carcinoma

Rafael B. Blasco, Sarah Francoz, David Santamarı́a et al. · Cancer Cell · 2011 · 297 citations · Full text

Medicine, Cancer Biology, Oncology +10