Matthew Holderfield

TNF primes endothelial cells for angiogenic sprouting by inducing a tip cell phenotype

Richard C.A. Sainson, Douglas A. Johnston, Henry C. Chu et al. · Blood · 2008 · 323 citations · Full text

Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy

Matthew Holderfield, Bianca J. Lee, Jingjing Jiang et al. · Nature · 2024 · 268 citations · Full text

Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers

Jingjing Jiang, Lingyan Jiang, Benjamin J. Maldonato et al. · Cancer Discovery · 2024 · 231 citations · Full text

Cell‐autonomous notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesis

Richard C.A. Sainson, Jason Aoto, Martin N. Nakatsu et al. · The FASEB Journal · 2005 · 227 citations

Cell‐autonomous Notch, Endothelial Cells, Cellular Physiology +16

K-Ras Promotes Tumorigenicity through Suppression of Non-canonical Wnt Signaling

Man-Tzu Wang, Matthew Holderfield, Jacqueline Galeas et al. · Cell · 2015 · 189 citations · Full text

Signaling Pathway, Medicine, Tumor Suppressor +5