Concepedia

Stabilization of HIF-2α through redox regulation of mTORC2 activation and initiation of mRNA translation

B. K. Nayak, Denis Féliers, Sunil Sudarshan, William E. Friedrichs, Robert T. Day, David New, John P. Fitzgerald, Assaad A. Eid, Thomas S. DeNapoli, Dipen J. Parekh,

Oncogene · 2012 · 56 citations · 21 references

DOI

Concepts

References

21

Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2

Morris E. Feldman, Beth Apsel, Aino Uotila et al. · PLoS Biology · 2009 · 1.1K citations · Full text

, , +17

Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

A. Lazaris-Karatzas, Kathleen S. Montine, Nahum Sonenberg · Nature · 1990 · 959 citations

, , +14

Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy

Hans-Guido Wendel, Elisa de Stanchina, Jordan S. Fridman et al. · Nature · 2004 · 947 citations

, , +14

Pivotal Role of mTOR Signaling in Hepatocellular Carcinoma

Augusto Villanueva, Derek Y. Chiang, Pippa Newell et al. · Gastroenterology · 2008 · 728 citations · Full text

, , +17

Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling

Tsuneo Ikenoue, Ken Inoki, Qian Yang et al. · The EMBO Journal · 2008 · 608 citations · Full text

, , +13