The translational landscape of mTOR signalling steers cancer initiation and metastasis

Andrew C. Hsieh, Yi Liu, Merritt P. Edlind, +16

Nature

Tumor BiologySignal TransductionSignaling PathwayCell RegulationMedicine +8

Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2

Morris E. Feldman, Beth Apsel, Aino Uotila, +4

PLoS Biology

Drug TargetMrna TranslationMolecular BiologyPharmacotherapyChemical Biology +22

Circular RNAs are long-lived and display only minimal early alterations in response to a growth factor

Yehoshua Enuka, Mattia Lauriola, Morris E. Feldman, +3

Nucleic Acids Research

EngineeringGeneticsEpigeneticsWidespread CirclesGrowth Factor +15

Imaging actin and dynamin recruitment during invagination of single clathrin-coated pits

Christien J. Merrifield, Morris E. Feldman, Lei Wan, +1

Nature Cell Biology

UrologySingle Clathrin-coated PitsCytoskeletonSurgeryMedicine +1

Genetic Dissection of the Oncogenic mTOR Pathway Reveals Druggable Addiction to Translational Control via 4EBP-eIF4E

Andrew C. Hsieh, Maria Da Costa, Ornella Zollo, +6

Cancer Cell

Molecular NeuroscienceAddictionGeneticsGenetic DissectionMedicine +7

A Membrane Marker Leaves Synaptic Vesicles in Milliseconds after Exocytosis in Retinal Bipolar Cells

David Zenisek, Jürgen A. Steyer, Morris E. Feldman, +1

Neuron

Ganglion CellPhotoreceptor CellRetinaOphthalmologyRetinal Bipolar Cells +6

Constitutive mTORC1 activation by a herpesvirus Akt surrogate stimulates mRNA translation and viral replication

Uyanga Chuluunbaatar, Richard J. Roller, Morris E. Feldman, +3

Genes & Development

mTOR Complex-2 Activates ENaC by Phosphorylating SGK1

Ming Lu, Jian Wang, Kevin T. Jones, +6

Journal of the American Society of Nephrology

Hm KinaseMolecular PhysiologySignal TransductionSignaling PathwayMedicine +11

Stretch-induced Calcium Release in Smooth Muscle

Guangju Ji, Robert Barsotti, Morris E. Feldman, +1

The Journal of General Physiology

Diurnal suppression of EGFR signalling by glucocorticoids and implications for tumour progression and treatment

Mattia Lauriola, Yehoshua Enuka, Amit Zeisel, +17

Nature Communications